Eye drops are liquid drops applied directly to the surface of the eye, usually in small amounts such as a single drop or a few drops. Eye drops may also contain one or more medications to treat a wide variety of eye diseases. As the eyes are so delicate, it is important that the eye drop packaging be user-friendly in order to easily dispense the treatment.
Eye drops have a lower risk of side effects than oral medicines, and such risk can be further minimized by occluding the lacrimal punctum for a short time after instilling drops.
Although most bottles of eye drops contain preservatives to inhibit contamination once open, these will not prevent contamination indefinitely. Ophthalmologists recommend keeping bottles for no longer than three months after opening. Eye drops that contain no preservatives are usually packaged in single-use tube vials and preservative-free eye drop bottles.
BONA's eye drop bottles
Ophthalmic products require stricter microbiological safety and material reliability. BONA offers various options for different customers and formulations. Apart from traditional sterilized eye drop bottles, 0.22micron filter membrane preservative-free systems can be commercialized.
What are the different options for ophthalmic products?
'Ordinary' eye drop bottles
Main Parameters:
- Bottle Volume: 5ml, 9ml, 10ml, 15ml
- Tamper-evident cap design
- Materials: LDPE, HDPE, PP, PET.
- Produced in Class D and Class C+A clean rooms
- Sterilization methods: EO, E-beam or Gamma irradiation
- Complies with CP, EP, USP food & drug direct contact regulations
Bottle no. | Capacity | Component / Material | Product ref. |
1 | 5ml | Cap - PP, Dropper - PP, Bottle - LDPE | BONA5664AAC |
2 | 10ml | Cap - PP, Dropper - PP, Bottle - LDPE | BONA5662A6C |
3 | 5ml | Cap - PP, Dropper - PP, Bottle - LDPE | BONA4R0399F |
4 | 5ml | Cap - HDPE, Dropper - LDPE, Bottle - PP | BONA5722A6C |
5 | 5ml | Cap - HDPE, Dropper - LDPE, Bottle - PP | BONA5722A6C |
6 | 10ml | Cap - PP, Dropper - PE, Bottle - PET | BONA4R0295F |
7 | 9ml | Cap - PE, Dropper - PE, Bottle - PE | BONA4R0397F |
8 | 15ml | Cap - PE, Dropper - PE, Bottle - PE | BONA4R0398F |
Minidose/monodose eye drop vials
Main Parameters:
- Volume: 1ml single-dose for Minidose eye drop bottle/oral vaccine
- Can be customized with embossing
- Sterilization methods: EO, E-beam or Gamma irradiation
- Complies with CP, EP, USP food & drug direct contact regulations
- Applications: small volume eye drop bottle, serums, and vaccines etc.
Preservative-free eye drop bottle
Main Parameters:
- Air filter membrane
- Passed microbiological challenging test
- Bottle volume: 5ml, 7ml, 10ml